Can defective interfering RNAs affect the live attenuated influenza vaccine?
نویسندگان
چکیده
منابع مشابه
Live attenuated influenza vaccine--a review.
Owing to the variability of influenza viruses, vaccine composition needs to be up-dated annually. As many variables can influence their efficacy, vaccines are still considered "sub-optimal". Many studies have been carried out in recent years to improve vaccines. In particular, researchers and vaccine-producing corporations have focused on developing a live vaccine. Among the candidate vaccines,...
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The live attenuated influenza vaccine FluMist® was withdrawn in the USA by the Centers for Disease Control and Prevention after its failure to provide adequate protective immunity during 2013-2016. The vaccine uses attenuated core type A and type B viruses, reconfigured each year to express the two major surface antigens of the currently circulating viruses. Here Fluenz™ Tetra, the European ver...
متن کاملAcceptability of intranasal live attenuated influenza vaccine, influenza knowledge and vaccine intent in The Gambia
BACKGROUND The burden of influenza is increasingly recognised in Africa. The WHO recommends introducing influenza vaccination to high-risk groups: pregnant women, children <5 years, and the elderly. The Gambia currently has no influenza vaccination policy, but the NASIMMUNE study, a clinical trial of intranasal live attenuated influenza vaccines (LAIV) in young children provided an opportunity ...
متن کاملMaternal outcomes among pregnant women receiving live attenuated influenza vaccine
BACKGROUND Although the live attenuated influenza vaccine (LAIV) prescribing information contains warnings/precautions against use during pregnancy, administration of LAIV to pregnant women does occur. Data regarding maternal outcomes after LAIV administration during pregnancy are limited. OBJECTIVES Maternal outcomes after LAIV vaccination during pregnancy were examined. METHODS Data from ...
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Swine influenza (SI) is an acute, highly contagious, respiratory disease of swine caused by influenza A viruses. In addition, SI infections possess significant human public health concerns as they may serve as intermediate host for the generation of new pandemic viruses. Vaccination is still the primary method for the prevention and control of SI. Currently, commercially available vaccines agai...
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ژورنال
عنوان ژورنال: The Lancet Infectious Diseases
سال: 2017
ISSN: 1473-3099
DOI: 10.1016/s1473-3099(17)30637-0